Group-specific discriminant analysis reveals statistically validated sex differences in lateralization of brain functional network

arXiv:2404.05781v1 Announce Type: cross
Abstract: Lateralization is a fundamental feature of the human brain, where sex differences have been observed. Conventional studies in neuroscience on sex-specific lateralization are typically conducted on univariate statistical comparisons between male and female groups. However, these analyses often lack effective validation of group specificity. Here, we formulate modeling sex differences in lateralization of functional networks as a dual-classification problem, consisting of first-order classification for left vs. right functional networks and second-order classification for male vs. …

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