MixEHR-SurG: a joint proportional hazard and guided topic model for inferring mortality-associated topics from electronic health records

arXiv:2312.13454v2 Announce Type: replace
Abstract: Existing survival models either do not scale to high dimensional and multi-modal data or are difficult to interpret. In this study, we present a supervised topic model called MixEHR-SurG to simultaneously integrate heterogeneous EHR data and model survival hazard. Our contributions are three-folds: (1) integrating EHR topic inference with Cox proportional hazards likelihood; (2) integrating patient-specific topic hyperparameters using the PheCode concepts such that each topic can be identified with exactly one PheCode-associated phenotype; (3) …

arxiv cs.lg electronic electronic health records health mortality records stat.me topics type