Unsupervised Generation of Pseudo Normal PET from MRI with Diffusion Model for Epileptic Focus Localization

[$^{18}$F]fluorodeoxyglucose (FDG) positron emission tomography (PET) has emerged as a crucial tool in identifying the epileptic focus, especially in cases where magnetic resonance imaging (MRI) diagnosis yields indeterminate results. FDG PET can provide the metabolic information of glucose and help identify abnormal areas that are not easily found through MRI. However, the effectiveness of FDG PET-based assessment and diagnosis depends on the selection of a healthy control group. The healthy control group typically consists of healthy individuals similar to epilepsy …

cases cs.cv diagnosis diffusion diffusion model focus identify imaging information localization mri normal pet tool unsupervised