AI Model TRTpred Revolutionizes Cancer Immunotherapies

Researchers have developed an artificial intelligence (AI) model, called TRTpred, that can accurately predict tumor-killing immune cells. The AI model was trained using gene-expression profiles from 235 T cell receptors (TCRs) of patients with metastatic melanoma. The model was able to accurately identify tumor-reactive T cells with a 90% accuracy rate. The researchers further refined the selection process by applying algorithms to identify T cells with high binding strength to tumor antigens. The combination of TRTpred and the algorithmic filters, …

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