Automated causal inference in application to randomized controlled clinical trials. (arXiv:2201.05773v2 [stat.ME] UPDATED)

Randomized controlled trials (RCTs) are considered as the gold standard for
testing causal hypotheses in the clinical domain. However, the investigation of
prognostic variables of patient outcome in a hypothesized cause-effect route is
not feasible using standard statistical methods. Here, we propose a new
automated causal inference method (AutoCI) built upon the invariant causal
prediction (ICP) framework for the causal re-interpretation of clinical trial
data. Compared to existing methods, we show that the proposed AutoCI allows to
efficiently determine the …

application arxiv causal inference clinical trials