BEND: Benchmarking DNA Language Models on biologically meaningful tasks

arXiv:2311.12570v3 Announce Type: replace-cross
Abstract: The genome sequence contains the blueprint for governing cellular processes. While the availability of genomes has vastly increased over the last decades, experimental annotation of the various functional, non-coding and regulatory elements encoded in the DNA sequence remains both expensive and challenging. This has sparked interest in unsupervised language modeling of genomic DNA, a paradigm that has seen great success for protein sequence data. Although various DNA language models have been proposed, evaluation tasks often …

arxiv benchmarking cs.lg dna language language models q-bio.gn tasks type