[D] [P] Questions about the usability of Shapley values on large feature spaces.

Hello! I am planning a research project which involves creating a classification DNN that takes in a frame from a molecular dynamics simulation of a protein which encodes each amino acid's level of energetic interaction and tries to predict whether that frame came from protein state "A" or protein state "B." I want to analyze the feature importance, that is, the importance of amino acid's energetic interaction level for making the classification prediction. Although I have heard some interesting applications …

feature machinelearning usability values