Web: http://arxiv.org/abs/2105.05758

June 17, 2022, 1:13 a.m. | M.Sadegh Saberian, Kathleen P. Moriarty, Andrea D. Olmstead, Christian Hallgrimson, François Jean, Ivan R. Nabi, Maxwell W. Libbrecht, Ghassan Ha

cs.CV updates on arXiv.org arxiv.org

Drug repurposing can accelerate the identification of effective compounds for
clinical use against SARS-CoV-2, with the advantage of pre-existing clinical
safety data and an established supply chain. RNA viruses such as SARS-CoV-2
manipulate cellular pathways and induce reorganization of subcellular
structures to support their life cycle. These morphological changes can be
quantified using bioimaging techniques. In this work, we developed DEEMD: a
computational pipeline using deep neural network models within a multiple
instance learning framework, to identify putative treatments effective …

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