Detailed Balanced Chemical Reaction Networks as Generalized Boltzmann Machines. (arXiv:2205.06313v1 [q-bio.MN])

Can a micron sized sack of interacting molecules understand, and adapt to a
constantly-fluctuating environment? Cellular life provides an existence proof
in the affirmative, but the principles that allow for life's existence are far
from being proven. One challenge in engineering and understanding biochemical
computation is the intrinsic noise due to chemical fluctuations. In this paper,
we draw insights from machine learning theory, chemical reaction network
theory, and statistical physics to show that the broad and biologically
relevant class of …

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