ESCADA: Efficient Safety and Context Aware Dose Allocation for Precision Medicine. (arXiv:2111.13415v2 [cs.LG] UPDATED)

Finding an optimal individualized treatment regimen is considered one of the
most challenging precision medicine problems. Various patient characteristics
influence the response to the treatment, and hence, there is no
one-size-fits-all regimen. Moreover, the administration of an unsafe dose
during the treatment can have adverse effects on health. Therefore, a treatment
model must ensure patient \emph{safety} while \emph{efficiently} optimizing the
course of therapy. We study a prevalent medical problem where the treatment
aims to keep a physiological variable in a …

arxiv context medicine precision precision medicine safety