Generative AI for Controllable Protein Sequence Design: A Survey

arXiv:2402.10516v1 Announce Type: cross
Abstract: The design of novel protein sequences with targeted functionalities underpins a central theme in protein engineering, impacting diverse fields such as drug discovery and enzymatic engineering. However, navigating this vast combinatorial search space remains a severe challenge due to time and financial constraints. This scenario is rapidly evolving as the transformative advancements in AI, particularly in the realm of generative models and optimization algorithms, have been propelling the protein design field towards an unprecedented revolution. …

abstract arxiv challenge constraints cs.ai cs.lg design discovery diverse drug discovery engineering fields financial generative novel protein protein engineering q-bio.bm search space survey type vast