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Group-specific discriminant analysis reveals statistically validated sex differences in lateralization of brain functional network
April 10, 2024, 4:42 a.m. | Shuo Zhou, Junhao Luo, Yaya Jiang, Haolin Wang, Haiping Lu, Gaolang Gong
cs.LG updates on arXiv.org arxiv.org
Abstract: Lateralization is a fundamental feature of the human brain, where sex differences have been observed. Conventional studies in neuroscience on sex-specific lateralization are typically conducted on univariate statistical comparisons between male and female groups. However, these analyses often lack effective validation of group specificity. Here, we formulate modeling sex differences in lateralization of functional networks as a dual-classification problem, consisting of first-order classification for left vs. right functional networks and second-order classification for male vs. …
abstract analysis arxiv brain cs.lg differences feature functional however human network neuroscience q-bio.nc sex statistical studies type validation
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