Web: http://arxiv.org/abs/2209.07527

Sept. 19, 2022, 1:11 a.m. | Emilio Dorigatti, Bernd Bischl, Benjamin Schubert

cs.LG updates on arXiv.org arxiv.org

Accurate in silico modeling of the antigen processing pathway is crucial to
enable personalized epitope vaccine design for cancer. An important step of
such pathway is the degradation of the vaccine into smaller peptides by the
proteasome, some of which are going to be presented to T cells by the MHC
complex. While predicting MHC-peptide presentation has received a lot of
attention recently, proteasomal cleavage prediction remains a relatively
unexplored area in light of recent advances in high-throughput mass
spectrometry-based …

arxiv bio positive prediction

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