Metareview-informed Explainable Cytokine Storm Detection during CAR-T cell Therapy. (arXiv:2206.10612v1 [q-bio.QM])

Cytokine release syndrome (CRS), also known as cytokine storm, is one of the
most consequential adverse effects of chimeric antigen receptor therapies that
have shown promising results in cancer treatment. When emerging, CRS could be
identified by the analysis of specific cytokine and chemokine profiles that
tend to exhibit similarities across patients. In this paper, we exploit these
similarities using machine learning algorithms and set out to pioneer a
meta--review informed method for the identification of CRS based on specific …

arxiv bio cell therapy detection