May 12, 2023, 12:46 a.m. | Ana Lawry Aguila, James Chapman, Andre Altmann

cs.CV updates on arXiv.org arxiv.org

One of the challenges of studying common neurological disorders is disease
heterogeneity including differences in causes, neuroimaging characteristics,
comorbidities, or genetic variation. Normative modelling has become a popular
method for studying such cohorts where the 'normal' behaviour of a
physiological system is modelled and can be used at subject level to detect
deviations relating to disease pathology. For many heterogeneous diseases, we
expect to observe abnormalities across a range of neuroimaging and biological
variables. However, thus far, normative models have …

arxiv become challenges disease imaging modelling multiple neuroimaging normal popular studying variational autoencoders

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