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Predicting microsatellite instability and key biomarkers in colorectal cancer from H&E-stained images: Achieving SOTA with Less Data using Swin Transformer. (arXiv:2208.10495v1 [q-bio.QM])
Aug. 24, 2022, 1:10 a.m. | Bangwei Guo, Jitendra Jonnagaddala, Hong Zhang, Xu Steven Xu
cs.LG updates on arXiv.org arxiv.org
Artificial intelligence (AI) models have been developed for predicting
clinically relevant biomarkers, including microsatellite instability (MSI), for
colorectal cancers (CRC). However, the current deep-learning networks are
data-hungry and require large training datasets, which are often lacking in the
medical domain. In this study, based on the latest Hierarchical Vision
Transformer using Shifted Windows (Swin-T), we developed an efficient workflow
for biomarkers in CRC (MSI, hypermutation, chromosomal instability, CpG island
methylator phenotype, BRAF, and TP53 mutation) that only required relatively
small …
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