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Self-supervised multimodal neuroimaging yields predictive representations for a spectrum of Alzheimer's phenotypes. (arXiv:2209.02876v1 [cs.LG])
Sept. 8, 2022, 1:11 a.m. | Alex Fedorov, Eloy Geenjaar, Lei Wu, Tristan Sylvain, Thomas P. DeRamus, Margaux Luck, Maria Misiura, R Devon Hjelm, Sergey M. Plis, Vince D. Calhoun
cs.LG updates on arXiv.org arxiv.org
Recent neuroimaging studies that focus on predicting brain disorders via
modern machine learning approaches commonly include a single modality and rely
on supervised over-parameterized models.However, a single modality provides
only a limited view of the highly complex brain. Critically, supervised models
in clinical settings lack accurate diagnostic labels for training. Coarse
labels do not capture the long-tailed spectrum of brain disorder phenotypes,
which leads to a loss of generalizability of the model that makes them less
useful in diagnostic settings. …
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