Web: http://arxiv.org/abs/2201.08706

Jan. 24, 2022, 2:10 a.m. | Poulami Somanya Ganguly, Felix Lucka, Holger Kohr, Erik Franken, Hermen Jan Hupkes, K Joost Batenburg

cs.CV updates on arXiv.org arxiv.org

Tilt-series alignment is crucial to obtaining high-resolution reconstructions
in cryo-electron tomography. Beam-induced local deformation of the sample is
hard to estimate from the low-contrast sample alone, and often requires
fiducial gold bead markers. The state-of-the-art approach for deformation
estimation uses (semi-)manually labelled marker locations in projection data to
fit the parameters of a polynomial deformation model. Manually-labelled marker
locations are difficult to obtain when data are noisy or markers overlap in
projection data. We propose an alternative mathematical approach for …

algorithm arxiv localization

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