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Topological Data Analysis in Time Series: Temporal Filtration and Application to Single-Cell Genomics. (arXiv:2204.14048v1 [cs.LG])
cs.LG updates on arXiv.org arxiv.org
The absence of a conventional association between the cell-cell cohabitation
and its emergent dynamics into cliques during development has hindered our
understanding of how cell populations proliferate, differentiate, and compete,
i.e. the cell ecology. With the recent advancement of the single-cell
RNA-sequencing (RNA-seq), we can potentially describe such a link by
constructing network graphs that characterize the similarity of the gene
expression profiles of the cell-specific transcriptional programs, and
analyzing these graphs systematically using the summary statistics informed by
the …
analysis application arxiv data data analysis genomics series temporal time time series