What if We could Universally Edit Any Two Pieces of DNA? Meet ‘Bridge Editing’ and ‘Bridge RNA’: A Modular Approach to RNA-Guided Genetic Rearrangements in Bacteria

Genomic rearrangements are vital in genetic diversity, facilitated by enzymes involved in DNA repair and genetic material movement, such as transposases and recombinases. These enzymes are utilized by mobile genetic elements (MGEs) to mobilize DNA, ranging from site-specific to semi-random insertions and deletions. Insertion sequences (IS), found extensively in bacteria and archaea, typically employ transposases […]

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ai paper summary bacteria bridge diversity dna edit editing editors pick elements genomic material mobile modular repair rna staff tech news vital