Nuclei-Location Based Point Set Registration of Multi-Stained Whole Slide Images

arXiv:2404.17041v1 Announce Type: new
Abstract: Whole Slide Images (WSIs) provide exceptional detail for studying tissue architecture at the cell level. To study tumour microenvironment (TME) with the context of various protein biomarkers and cell sub-types, analysis and registration of features using multi-stained WSIs is often required. Multi-stained WSI pairs normally suffer from rigid and non-rigid deformities in addition to slide artefacts and control tissue which present challenges at precise registration. Traditional registration methods mainly focus on global rigid/non-rigid registration but …

abstract analysis architecture arxiv context cs.cv features images location normally protein registration set study studying type types