Deep Learning-Based Correction and Unmixing of Hyperspectral Images for Brain Tumor Surgery

Hyperspectral Imaging (HSI) for fluorescence-guided brain tumor resection enables visualization of differences between tissues that are not distinguishable to humans. This augmentation can maximize brain tumor resection, improving patient outcomes. However, much of the processing in HSI uses simplified linear methods that are unable to capture the non-linear, wavelength-dependent phenomena that must be modeled for accurate recovery of fluorophore abundances. We therefore propose two deep learning models for correction and unmixing, which can account for the nonlinear effects and produce …

augmentation brain cs.lg deep learning differences eess.iv humans images imaging linear non-linear patient processing simplified surgery visualization