Large scale paired antibody language models

arXiv:2403.17889v1 Announce Type: cross
Abstract: Antibodies are proteins produced by the immune system that can identify and neutralise a wide variety of antigens with high specificity and affinity, and constitute the most successful class of biotherapeutics. With the advent of next-generation sequencing, billions of antibody sequences have been collected in recent years, though their application in the design of better therapeutics has been constrained by the sheer volume and complexity of the data. To address this challenge, we present IgBert …

abstract antibody arxiv class cs.lg identify language language models next proteins q-bio.bm scale sequencing specificity type